Computational Biology - WMM9AM36
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Goals
This interdisciplinary course is designed for students with a
computational or mathematical background, providing them with the skills
necessary to move into bioinformatics and computational biology. The
objective is to provide an introduction to the modeling of biological
phenomena, and to present advanced software and mathematical tools for
the analysis of sequencing data.
Content Through a realistic bacterial outbreak scenario, the first part of the lecture will deal with omics biology from sequence to protein structure. Through a challenging project, you will need to leverage fundamental computational biology concepts and knowledge (standard tools like blast and standard biological databases) in order to implement your own algorithmic and statistical solution.
The second part of the course focuses on evolutionary biology and
population biology. The central concepts of the field are presented in a
computational form, with emphasis on methods for modeling and simulating
the phenomena studied. Through data analyses projects and critical
reading of research articles, the focus is put on modern research
questions (microbiome, drug discovery, etc) involving large datasets and
tools from artificial intelligence.
PrerequisitesBasic statistics (Poisson distribution), algorithmics (complexity), programming (python required, and R or matlab).
Tests Session one: Evaluation on project report and source code.
Session two: oral examination.
N1 = 0.5*E1a + 0.5*E1b
N2 = E2
The exam is given in english only 
Calendar The course exists in the following branches:
- Curriculum - Master in Applied Mathematics - Semester 9 (this course is given in english only
)
see
the course schedule for 2022-2023
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Date of update September 21, 2022